Pharmaceutical Estradiol Valerate 2mg x 28

£29.99

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Estradiol valerate x 28

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Estradiol Valerate 2mg Drug Classification: 

Estrogen; Hormonal medication
Active substance: Estradiol Valerate
Form: 2mg x 28 tablets
Active half-life: Approximately 13-17 hours
Acne: Rarely
Water retention: Possible, but uncommon
Hepatotoxicity: Low
Aromatization: Yes

What is Pharmaceutical Estradiol Valerate 2mg?

Pharmaceutical Estradiol Valerate 2mg is a medication containing estradiol valerate, a synthetic form of estrogen. Estradiol is the primary female sex hormone and is essential for various physiological functions in both men and women. Estradiol valerate is commonly prescribed for hormone replacement therapy (HRT) in menopausal women to alleviate symptoms such as hot flashes, vaginal dryness, and mood swings. It is also used to treat conditions like osteoporosis and hormonal imbalances.

Recommended Dosage for Pharmaceutical Estradiol Valerate 2mg

The recommended dosage of Pharmaceutical Estradiol Valerate 2mg should be determined by a healthcare professional based on the individual’s medical history, symptoms, and response to treatment. Typically, it is taken orally once daily, with or without food. Dosage adjustments may be necessary depending on the patient’s age, hormone levels, and the severity of symptoms. It is essential to follow the prescribed dosage regimen to achieve the desired therapeutic effects while minimizing the risk of side effects.

How Does Pharmaceutical Estradiol Valerate 2mg Work?

Pharmaceutical Estradiol Valerate 2mg works by supplementing the body with estradiol, a natural hormone produced by the ovaries in women. Estradiol binds to estrogen receptors in various tissues, including the brain, uterus, bone, and breasts, exerting its effects on these organs. In menopausal women, estradiol levels decline, leading to symptoms such as hot flashes and vaginal dryness. By replacing estradiol with estradiol valerate, this medication helps alleviate these symptoms and restores hormonal balance.

Benefits of Taking Pharmaceutical Estradiol Valerate 2mg

  • Relief from Menopausal Symptoms: Alleviates hot flashes, night sweats, vaginal dryness, and mood swings associated with menopause.
  • Bone Health: Helps maintain bone density and reduce the risk of osteoporosis.
  • Urogenital Health: Improves vaginal health by reducing dryness and discomfort.
  • Cardiovascular Protection: May have cardiovascular benefits when used in conjunction with progesterone.
  • Hormone Replacement: Restores estrogen levels in women with hormonal deficiencies due to menopause or other conditions.

When Should You Take Pharmaceutical Estradiol Valerate 2mg?

Pharmaceutical Estradiol Valerate 2mg should be taken as prescribed by your healthcare provider. It is typically used for hormone replacement therapy (HRT) in menopausal women experiencing symptoms such as hot flashes, vaginal dryness, and mood swings. Additionally, it may be used for conditions like osteoporosis prevention, primary ovarian failure, and estrogen replacement in women with hypogonadism or those undergoing transgender hormone therapy.

When Should You Not Take Pharmaceutical Estradiol Valerate 2mg?

You should not take Pharmaceutical Estradiol Valerate 2mg if you have any of the following conditions:

  • History of Hormone-Sensitive Cancers: If you have or have had breast cancer, uterine cancer, or any other estrogen-dependent tumors.
  • Unexplained Vaginal Bleeding: If you experience any unexplained vaginal bleeding, it should be evaluated by a healthcare provider before starting treatment.
  • Blood Clot Disorders: If you have a history of blood clots, such as deep vein thrombosis (DVT), pulmonary embolism (PE), or other clotting disorders.
  • Liver Disease: If you have significant liver disease or impaired liver function.
  • Heart Disease or Stroke: If you have a history of heart disease, stroke, or other cardiovascular conditions.
  • Pregnancy or Breastfeeding: Estradiol valerate should not be used during pregnancy or breastfeeding due to potential risks to the fetus or nursing infant.

What is the Mechanism of Pharmaceutical Estradiol Valerate 2mg?

Pharmaceutical Estradiol Valerate 2mg works by providing estradiol, a synthetic form of the naturally occurring female hormone estrogen. Once administered, estradiol valerate is converted into estradiol in the body, where it binds to estrogen receptors in various tissues, including the reproductive organs, breast tissue, bones, liver, and brain. This binding regulates the transcription of specific genes involved in the development and maintenance of female secondary sexual characteristics, reproductive system health, and overall hormonal balance. By supplementing declining estradiol levels, particularly in menopausal women, estradiol valerate alleviates symptoms such as hot flashes, night sweats, and vaginal dryness, while also supporting bone density, reducing the risk of osteoporosis, and promoting cardiovascular health. This mechanism ensures a steady release of estradiol, helping maintain consistent hormone levels and improving the quality of life for individuals with hormonal imbalances.

Uses of Pharmaceutical Estradiol Valerate 2mg

  • Hormone Replacement Therapy: Used in menopausal women to replace declining estrogen levels.
  • Osteoporosis Prevention and Treatment: Helps maintain bone density and reduce the risk of fractures.
  • Primary Ovarian Failure: Used to supplement estrogen in women with ovarian insufficiency.
  • Hypogonadism: Treatment of estrogen deficiency in women with hypogonadism.
  • Transgender Hormone Therapy: Part of feminizing hormone therapy for transgender women.

Warnings and Precautions for Pharmaceutical Estradiol Valerate 2mg

Before using Pharmaceutical Estradiol Valerate 2mg, inform your healthcare provider of any medical conditions you have, especially if you have a history of breast cancer, uterine cancer, blood clots, heart disease, or liver problems. Discuss any medications or supplements you are taking, as they may interact with estradiol valerate. Regular monitoring of hormone levels and mammograms may be recommended during treatment. Stop taking the medication and seek medical attention if you experience symptoms of a blood clot or other serious side effects.

Side Effects of Pharmaceutical Estradiol Valerate 2mg

  • Common Side Effects:
    • Breast tenderness
    • Headache
    • Nausea
    • Irregular vaginal bleeding
    • Fluid retention
  • Serious Side Effects:
    • Blood clots
    • Stroke
    • Heart attack
    • Breast cancer
    • Endometrial cancer

Drug Interactions of Pharmaceutical Estradiol Valerate 2mg

Pharmaceutical Estradiol Valerate 2mg may interact with certain medications, including blood thinners, corticosteroids, anticonvulsants, and herbal supplements like St. John’s wort. Inform your healthcare provider of all medications and supplements you are taking to avoid potential interactions. Adjustments in dosage or alternative treatments may be necessary to manage these interactions effectively.

Storage for Pharmaceutical Estradiol Valerate 2mg

Store Pharmaceutical Estradiol Valerate 2mg at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use the medication past its expiration date. Dispose of unused or expired medication according to local regulations.

Where to Buy Pharmaceutical Estradiol Valerate 2mg?

Pharmaceutical Estradiol Valerate 2mg can be purchased from authorized retailers such as Steroid Direct UK. Ensure you buy from reputable sources to guarantee the authenticity and quality of the product. Verify local regulations regarding the purchase and use of prescription medications.

Frequently Asked Questions (FAQs)

  1. What is Pharmaceutical Estradiol Valerate 2mg used for?
    • Pharmaceutical Estradiol Valerate 2mg is primarily used in hormone replacement therapy (HRT) for menopausal women to alleviate symptoms such as hot flashes, vaginal dryness, and mood swings. It may also be prescribed for other conditions such as osteoporosis and hormonal imbalances.
  2. How should I take Pharmaceutical Estradiol Valerate 2mg?
    • Take Pharmaceutical Estradiol Valerate 2mg orally, usually once daily with or without food, as directed by your healthcare provider. Follow the prescribed dosage and instructions carefully for optimal results.
  3. Are there any side effects associated with Pharmaceutical Estradiol Valerate 2mg?
    • Common side effects of Pharmaceutical Estradiol Valerate 2mg may include breast tenderness, headache, nausea, irregular vaginal bleeding, and fluid retention. Serious side effects such as blood clots, stroke, heart attack, and certain cancers may occur. Consult your healthcare provider if you experience any adverse reactions.
  4. Can Pharmaceutical Estradiol Valerate 2mg be used during pregnancy or breastfeeding?
    • Pharmaceutical Estradiol Valerate 2mg is generally not recommended during pregnancy or breastfeeding, as it may harm the fetus or nursing infant. Consult your healthcare provider before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.
  5. What should I do if I miss a dose of Pharmaceutical Estradiol Valerate 2mg?
    • If you miss a dose of Pharmaceutical Estradiol Valerate 2mg, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

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